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EXCLUSIVE: 111Skin Opens Stand-alone Spa in the Plaza Hotel

StaffBy StaffSeptember 26, 20253 Mins Read
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The skincare brand 111Skin is making a significant entry into the American market with the grand opening of its first stand-alone spa at the Plaza Hotel in New York City. This expansive 8,000 square foot space is designed to offer a wide array of treatments—from signature facials that pamper and nourish the skin to advanced technological therapies such as LED light therapy, cryotherapy, and the Exosome Regenerative Facial Treatment. This standout treatment employs ultrasound and LED technology along with exosomes, which are cellular components that play a vital role in tissue regeneration, underscoring the brand’s commitment to innovative skincare solutions.

In recent months, 111Skin has experienced remarkable growth, particularly in North America, signaling a promising trajectory for the brand. Co-founder Dr. Yannis Alexandrides expressed his enthusiasm about this progress, noting that the North American direct-to-consumer market is thriving. Vanessa Goddevrind, the brand’s CEO, attributed this success to their transparency about Dr. Alexandrides’ clinical practice and the unique formulation of their products, setting them apart in a crowded luxury skincare marketplace. The company’s focus on differentiation has evidently resonated with consumers who seek effective, scientifically backed skin treatments.

Coinciding with the spa’s opening, 111Skin launched a four-week treatment called the Exosome Face Lift, featuring a two-product set available for $825. This initiative signals the brand’s ability to innovate within a challenging luxury skincare market. Despite a dip in overall luxury skincare sales in the U.S., 111Skin has bucked the trend by providing groundbreaking solutions tailored to customer needs. Dr. Alexandrides emphasized that exosomes have already been utilized in his London clinic for three years. Only after achieving significant results with his patients did he feel ready to introduce the product to the retail market, highlighting the brand’s dedication to efficacy.

The decision to expand into New York’s wellness-centric environment is not just a strategic move to meet market demand; it mirrors the evolving trends in the skincare industry. “New York is the epicenter of wellness,” noted Dr. Alexandrides. With a robust recognition of the brand in North America, particularly among international travelers, establishing a presence at the Plaza Hotel is a vital step forward. Looking ahead, the brand has laid out a three-year plan for additional spa openings in other appealing markets, aiming to expand its footprint on both the East Coast and West Coast.

The new spa embodies the ethos of 111Skin, serving as an extension of their renowned surgery clinic at 111 Harley Street in London—but without Dr. Alexandrides practicing surgery in the U.S. While he holds a license to practice in New York, the focus remains on skincare and aesthetic treatments. The spa boasts nine dedicated treatment rooms and employs a skilled team of trained aestheticians and massage therapists, combining expertise with luxury. The treatment offerings are designed to reflect Dr. Alexandrides’ comprehensive understanding of facial aesthetics, along with the brand’s international experience across over 100 luxury spas.

Conclusively, stepping into the 111Skin spa is akin to entering a space where the science of skincare meets luxury treatment. Dr. Alexandrides envisions this location as the ultimate representation of their brand, where clients can expect a high standard of professionalism, scientifically formulated treatments, and a unique blend of techniques. This nuanced approach aims to not only set 111Skin apart in a competitive landscape but also create meaningful experiences for clients, fostering a deeper connection with the brand and its innovative offerings.

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